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What's trending

DrugBank top drugs
  1. Morphine
    An opioid agonist used for the relief of moderate to severe acute and chronic pain.
  2. Acetaminophen
    An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
  3. Acetylsalicylic acid
    A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
  4. Codeine
    An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
  5. Salbutamol
    A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
  6. Oxycodone
    An opioid used in the management of moderate to severe pain.
DrugBank top products
  1. Fortamet
    Fortamet is a prescription biguanide available in multiple countries including the United States. It was first marketed in 2004. It is available in an Oral Tablet, extended release. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00331">Metformin</a>, in its salt form Metformin hydrochloride. <a href="http://7x6e75r.pw/drugs/DB00331">Metformin</a> is a medication used with diet and exercise to control blood sugar in diabetes and is sometimes used to control high blood sugar in a disease called polycystic ovary syndrome (or PCOS).
  2. Norvasc
    Norvasc is a prescription dihydropyridine calcium channel blocker available in multiple countries including the United States, Canada, and Italy. It was first marketed in 1992. It is available in an Oral Tablet. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00381">Amlodipine</a>, in its salt form Amlodipine besylate. <a href="http://7x6e75r.pw/drugs/DB00381">Amlodipine</a> is a heart medication used to treat high blood pressure and chest pain caused by heart disease.
  3. Prilosec
    Prilosec is a prescription and over-the-counter proton pump inhibitor available in multiple countries including the United States and Canada. It was first marketed in 1990. It is available in an Oral Capsule, delayed release, an Oral Granule, delayed release, and an Oral Tablet, delayed release. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00338">Omeprazole</a>, in its salt form Omeprazole magnesium. <a href="http://7x6e75r.pw/drugs/DB00338">Omeprazole</a> is a medication used to improve the symptoms of heartburn, and to treat related conditions such as ulcers, tissue damage and infection with the bacteria called H. pylori.
  4. Truvada
    Truvada is a prescription HIV nucleoside analog reverse transcriptase inhibitor (HIV NRTI) available in multiple countries including the United States, Canada, Italy, and the EU. It was first marketed in 2004. It is available in an Oral Tablet, film-coated, an Oral Tablet, coated, and an Oral Tablet. It contains two active ingredients: <a href="http://7x6e75r.pw/drugs/DB00879">Emtricitabine</a> and <a href="http://7x6e75r.pw/drugs/DB00300">Tenofovir disoproxil</a>, in its salt form Tenofovir disoproxil fumarate. <a href="http://7x6e75r.pw/drugs/DB00879">Emtricitabine</a> is a medication used to treat and prevent HIV. <a href="http://7x6e75r.pw/drugs/DB00300">Tenofovir disoproxil</a> is a medication used to treat hepatitis B infection and to manage HIV infection.
  5. Zocor
    Zocor is a prescription HMG CoA-reductase inhibitor available in multiple countries including the United States, Canada, and Italy. It was first marketed in 1990. It is available in an Oral Tablet and an Oral Tablet, film-coated. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00641">Simvastatin</a>. <a href="http://7x6e75r.pw/drugs/DB00641">Simvastatin</a> is a medication used to treat high cholesterol and reduce the risk of cardiovascular disease including heart attacks and stroke.
  6. Humira
    Humira is a prescription tumor necrosis factor (TNF) blocker available in multiple countries including the United States, Canada, the EU, Italy, and Indonesia. It was first marketed in 2002. It is available in a Subcutaneous Injection. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00051">Adalimumab</a>. <a href="http://7x6e75r.pw/drugs/DB00051">Adalimumab</a> is a medication used to treat a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
  7. Herceptin
    Herceptin is a prescription HER2 receptor antagonist available in multiple countries including the United States, Canada, the EU, Italy, and Indonesia. It was first marketed in 1998. It is available in an Intravenous Injection and a Subcutaneous Injection. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00072">Trastuzumab</a>. <a href="http://7x6e75r.pw/drugs/DB00072">Trastuzumab</a> is an injectable medication used to treat certain types of cancers that overexpress the HER2 protein.
  8. Flonase
    Flonase is an over-the-counter corticosteroid available in multiple countries including the United States and Canada. It was first marketed in 1993. It is available in a Nasal Spray, metered. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00588">Fluticasone propionate</a>. <a href="http://7x6e75r.pw/drugs/DB00588">Fluticasone propionate</a> is a medication used to treat asthma, certain skin conditions, and a runny nose.
  9. Plan-B
    Plan-B is an over-the-counter progestin available in multiple countries including the United States and Canada. It was first marketed in 1999. It is available in an Oral Tablet. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00367">Levonorgestrel</a>. <a href="http://7x6e75r.pw/drugs/DB00367">Levonorgestrel</a> is a hormone used in birth control medications and at higher doses as an emergency birth control pill for up to 72 hours following sexual intercourse.
  10. Imodium
    Imodium is an over-the-counter opioid agonist available in multiple countries including the United States, Canada, Germany, Colombia, Italy, and Indonesia. It was first marketed in 1983. It is available in an Oral Capsule, an Oral Tablet, and an Oral Solution. It contains one active ingredient: <a href="http://7x6e75r.pw/drugs/DB00836">Loperamide</a>, in its salt form Loperamide hydrochloride. <a href="http://7x6e75r.pw/drugs/DB00836">Loperamide</a> is a medication used to treat diarrhea.
Featured Drug
Db14761

Remdesivir

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase (RdRp) enzyme complex for genomic replication, which can be inhibited by a class of drugs known as nucleoside analogues. Remdesivir (GS-5734) is an adenosine triphosphate analogue first described in the literature in 2016 as a potential treatment for Ebola.[A191379, A222393] Broad antiviral activity of remdesivir is suggested by its mechanism of action, and to date, it has demonstrated in vitro activity against the Arenaviridae, Flaviviridae, Filoviridae, Paramyxoviridae, Pneumoviridae, and Coronaviridae viral families. Remdesivir activity against the Coronaviridae family was first demonstrated in 2017, leading to considerable interest in remdesivir as a possible treatment for COVID-19.[A191427, A198810] Remdesivir was confirmed as a non-obligate chain terminator of RdRp from SARS-CoV-2 and the related SARS-CoV and MERS-CoV, and has been investigated in multiple COVID-19 clinical trials.[L12174, L12177] Based on aggregate data, remdesivir was granted an FDA Emergency Use Authorization (EUA) on May 1st, 2020. The FDA subsequently granted full approval for remdesivir as a COVID-19 treatment on October 22, 2020, while simultaneously updating the EUA to cover those patients not included under the approved indication. Remdesivir is currently marketed under the trademark name VEKLURY? by Gilead Sciences Inc. Remdesivir in combination with baricitinib for the treatment of COVID-19, was granted an FDA Emergency Use Authorization on 19 Novermber 2020.

Targets (4)
Featured Info

COVID-19 Information Dashboard

We've put together a COVID-19 Information Dashboard, to provide a comprehensive summary of relevant COVID-19 research, in an effort to help researchers find the information they need quickly and effectively.

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